By Wilhelm Max Wundt
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The medication should be discontinued immediately. D. Dermatological: Rash and urticaria are relatively common. Photosensitivity reactions may rarely occur. Potentially dangerous, but very rare, dermatological side effects include exfoliative dermatitis and toxic epidermal necrolysis (StevensJohnson syndrome), requiring immediate discontinuation of the drug. E. Anticholinergic: Carbamazepine has mild anticholinergic activity and may exacerbate glaucoma and prostatic hypertrophy. F. Cardiac: Uncommon side effects include AV conduction defects, arrhythmias, and congestive heart failure.
Clinical Guidelines: Rapid onset provides prompt relief. Clonazepam, has a long half-life and may be substituted for shorter acting benzodiazepines, such as alprazolam, in the treatment of benzodiazepine withdrawal and panic disorder. The long half-life of clonazepam allows for once-a-day dosing. Pregnancy: Category D. Clorazepate (Tranxene) Indications: Anxiety. 5 mg tablets. Pharmacology: Clorazepate is metabolized to desmethyldiazepam in the GI tract and absorbed in this active form. 5 mg tid or 15 mg qhs.
Patients may report waking up after 3-4 hours when blood level drops. It is not recommended for patients who have trouble maintaining sleep throughout the night. Use should be limited to 10 days. Use with caution in the elderly. References, see page 113. Non-Benzodiazepine Hypnotics Zolpidem (Ambien) Category: Non-benzodiazepine hypnotic. Mechanism: Binds to the GABA receptor but is a non-benzodiazepine. Indications: Insomnia. Preparations: 5, 10 mg tablets. Dosage: 10 mg qhs (5 mg for elderly).
Grundriss der Psychologie by Wilhelm Max Wundt
Categories: Psychology Counseling