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By Stephen Nowicki

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The difference is due to mismatch repair mechanisms associated with the replication process that detect errors shortly after they occur and replace an incorrectly matched base with a correct one. 1. DNA polymerase has its own error-checking process and usually replaces an incorrect base with the correct one. 2 billion base pairs. 2. Mismatch repair enzymes constantly inspect newly synthesized DNA for incorrect base pairings. When they discover a mistake, they cut out the incorrect base or section and let DNA polymerase replace the section.

When they discover a mistake, they cut out the incorrect base or section and let DNA polymerase replace the section. 3. As a result of complementary base pairing, finding errors should be simple, but determining the correct replacement must be difficult, because there is no way to know which base in a pair is the correct one. Molecular biologists discovered that DNA is ©2004 The Teaching Company Limited Partnership 53 4. gradually methylated as it ages, and mismatch repair enzymes use differences in methylation to determine which base is correct and which is not.

This term describes the process through which information is changed from its functionally useless form in DNA and RNA into the functionally useful form of proteins. IV. The Central Dogma provides a convenient framework for organizing our thinking about the molecular basis of genetic information. A. We have used the term gene loosely, but the Central Dogma makes clear that a gene must be, at least to a first approximation, a segment of DNA that carries the code for making a particular protein. B.

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Biology: The Science of Life by Stephen Nowicki

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Categories: Anatomy